A commentary on “Testosterone therapy in boys with constitutional delay of growth and puberty: a PubMed-based systematic review and exploratory meta-analysis”
Muqaddas Boltaboeva, Abdulhamid Haydarov, Lola Rakhmanova · 2026
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Description
Muqaddas Boltaboeva, Abdulhamid Haydarov, and Lola Rakhmanova comment on a review of testosterone treatment for boys with delayed puberty. The condition, a constitutional delay of growth and puberty, is a common cause of late development in boys. The review pooled past studies on whether hormone treatment speeds things up. The comment praises the effort, then adds cautions.
Family patterns show that genes weigh heavily on puberty timing. Yet the pooled studies rarely measured genetic background. That gap may explain part of the wide spread in results. Rare single-gene disorders can also mimic the common condition while needing different care. The writers urge future studies to record family and gene data. Treatment choices, they argue, should rest on that fuller picture.
Catalog record
| CREATOR | Muqaddas Boltaboeva, Abdulhamid Haydarov, Lola Rakhmanova |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 4 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |