Sentinel Lymph Node Positivity by Tumour Grade in Older Women With Breast Cancer: A Cross-Verified Retrospective Cohort Study
Raafat Mady, Omar Mady, Maryam Nazim, Gary Boland, Zuhair Saidan, Alexander Muacevic, John R Adler · 2026
Read Sentinel Lymph Node Positivity by Tumour Grade in Older Women With Breast Cancer: A Cross-Verified Retrospective Cohort Study by Raafat Mady, Omar Mady, Maryam Nazim, Gary Boland, Zuhair Saidan, Alexander Muacevic, John R Adler (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13646750.txt.
Description
Raafat Mady and six colleagues ask whether a sentinel lymph node biopsy can safely be skipped in older women with the most favorable breast cancers, using records from one British breast unit. Guidelines already question the routine biopsy for women over seventy with hormone-sensitive, early tumors. The team cross-checked hospital coding against pathology records for patients biopsied between January 2015 and December 2020. Ages were verified independently rather than assumed.
In the primary group of thirty-nine women with grade 1, small, hormone-positive tumors, the biopsy found spread in just three patients. Positivity rose in grade 2 disease and sat between the two in grade 3, a pattern read with care given the small numbers. All primary-group patients were followed at least five years. The authors argue the low yield supports selective omission of the biopsy in this narrow subgroup, sparing older women an operation that rarely changes their care.
Catalog record
| CREATOR | Raafat Mady, Omar Mady, Maryam Nazim, Gary Boland, Zuhair Saidan, Alexander Muacevic, John R Adler |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| LICENSE | This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provide |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |