Paternal leakage of mitochondrial DNA is genetically controlled in Drosophila

Maria-Eleni Parakatselaki, Stavroula Zapri, Sevasti Koursioti, Eirini Slavka Polovina, Emmanuel Ladoukakis · 2026

Read Paternal leakage of mitochondrial DNA is genetically controlled in Drosophila by Maria-Eleni Parakatselaki, Stavroula Zapri, Sevasti Koursioti, Eirini Slavka Polovina, Emmanuel Ladoukakis (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13643810.txt.

Description

Maria-Eleni Parakatselaki and four colleagues present a 2026 study showing that fathers' mitochondrial DNA leaking into offspring is genetically controlled in fruit flies. Mitochondrial DNA is normally inherited only from the mother, and leakage has been treated as random error.

Crossing several Drosophila simulans lines with a sister species, the team measured mixed mitochondrial types in hybrids. Leakage levels ran consistently within families, repeated across experiments, and ran higher in males than females. Estimated heritability was high, and wild-derived lines varied more than inbred stocks. The authors argue leakage is a governed trait with possible long-term effects on mitochondrial genome stability.

Catalog record

CREATORMaria-Eleni Parakatselaki, Stavroula Zapri, Sevasti Koursioti, Eirini Slavka Polovina, Emmanuel Ladoukakis
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE31 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13643810

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