Liver Dysfunction Assessed by Albumin – Bilirubin (ALBI) Score is Associated with Disturbed Cholesterol Profiles and Reduced Survival in Patients with Chronic Limb-Threatening Ischemia
Kentaro Inoue, Shinichiro Yoshino, Yutaka Matsubara, Tadashi Furuyama, Toshihiro Onohara · 2026
Read Liver Dysfunction Assessed by Albumin – Bilirubin (ALBI) Score is Associated with Disturbed Cholesterol Profiles and Reduced Survival in Patients with Chronic Limb-Threatening Ischemia by Kentaro Inoue, Shinichiro Yoshino, Yutaka Matsubara, Tadashi Furuyama, Toshihiro Onohara (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13643005.txt.
Description
Kentaro Inoue and co-authors show that a liver score forecasts survival in patients with dying limbs. Chronic limb-threatening ischemia starves legs of blood; liver health quietly shapes who survives it. Their 2026 study computes the albumin-bilirubin score for 263 patients with below-knee disease treated over a decade. A data-driven cutoff splits high and low liver-risk groups. Fibrosis and cholesterol profiles are compared beside three-year survival.
The high-score group skews older, frailer, and more heart-burdened. Their fibrosis index runs higher and every cholesterol fraction lower. Three-year survival lands at 36 percent against 57 in the low group. Matching on other traits keeps the gap. Liver function, the team argues, belongs in limb prognosis talks.
Catalog record
| CREATOR | Kentaro Inoue, Shinichiro Yoshino, Yutaka Matsubara, Tadashi Furuyama, Toshihiro Onohara |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |