Noninvasive Trans-Spinal Direct Current Stimulation Improves Breathing in Mice Modeling an Obesity-Associated Central Hypoventilation Syndrome

Roman Delucenay-Clarke, Alexis Casciato, Marlène Bret, Manon Reverdy, Alain Frugière, Frédéric Blond, Noémie Bonneau, Elodie Reboussin, Annabelle Réaux-Le Goazigo, Xavier Guillonneau, Jean-Charles Lamy, Thomas Similowski, Marie-Cécile Niérat, Florence Cayetanot, Laurence Bodineau · 2026

Read Noninvasive Trans-Spinal Direct Current Stimulation Improves Breathing in Mice Modeling an Obesity-Associated Central Hypoventilation Syndrome by Roman Delucenay-Clarke, Alexis Casciato, Marlène Bret, Manon Reverdy, Alain Frugière, Frédéric Blond, Noémie Bonneau, Elodie Reboussin, Annabelle Réaux-Le Goazigo, Xavier Guillonneau, Jean-Charles Lamy, Thomas Similowski, Marie-Cécile Niérat, Florence Cayetanot, Laurence Bodineau (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13642236.txt.

Description

Roman Delucenay-Clarke and fourteen colleagues present a 2026 research letter on noninvasive spinal stimulation for weak breathing in obesity hypoventilation syndrome. In this disorder, obesity combines with blunted central breathing drive, and no curative treatment exists.

The team had earlier shown that gentle direct current applied over the upper neck spine raised diaphragm excitability and breath size in healthy people. Here they test the same trans-spinal approach in mice modeling the syndrome's central breathing failure. The letter frames stimulation-induced plasticity as a possible route to restore ventilation without drugs or machines, pending what the animal results show.

Catalog record

CREATORRoman Delucenay-Clarke, Alexis Casciato, Marlène Bret, Manon Reverdy, Alain Frugière, Frédéric Blond, Noémie Bonneau, Elodie Reboussin, Annabelle Réaux-Le Goazigo, Xavier Guillonneau, Jean-Charles Lamy, Thomas Similowski, Marie-Cécile Niérat, Florence Cayetanot, Laurence Bodineau
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE23 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13642236

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