Time to Effective Antibiotic Therapy and Clinical Outcomes in Bloodstream Infections With ESBL-Producing Enterobacterales: A Retrospective Multicenter Cohort Study
Thomas Sahlström Månsson, Alice Askemyr, Lisa Mellhammar · 2026
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Description
Thomas Sahlström Månsson and two colleagues present a Swedish cohort study on timing of effective antibiotics in bloodstream infections caused by drug-resistant bacteria. Patients often start on a drug the bacteria resist, and whether that early mismatch harms them was uncertain.
The multicenter review covered 644 patients in southern Sweden from 2013 to 2022, and nearly half received ineffective first therapy for over a day. That delay showed no significant link with thirty-day death, intensive care admission after adjustment, or longer hospital stay. The authors say the finding could support holding back the strongest antibiotics in low-resistance settings.
Catalog record
| CREATOR | Thomas Sahlström Månsson, Alice Askemyr, Lisa Mellhammar |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |