Differential Assembly of Native Epithelial Sodium Channel Complexes Across Mouse Epithelial Tissues
Arpita Bharadwaj, Joshua N. Curry, Xiao-Tong Su, Romina Barria Maturana, James A. McCormick, David H. Ellison, Isabelle Baconguis · 2026
Read Differential Assembly of Native Epithelial Sodium Channel Complexes Across Mouse Epithelial Tissues by Arpita Bharadwaj, Joshua N. Curry, Xiao-Tong Su, Romina Barria Maturana, James A. McCormick, David H. Ellison, Isabelle Baconguis (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13641531.txt.
Description
Arpita Bharadwaj and six colleagues present a 2026 study of how the epithelial sodium channel is assembled inside real mouse tissues. This channel controls sodium movement across surface linings and helps govern fluid balance, blood pressure, and airway moisture.
Most knowledge comes from lab-grown cells forced to overproduce channel parts, which may miss how tissues build the channel naturally. The team engineered a mouse line carrying a tagged channel subunit so intact native complexes could be pulled out and examined across different epithelial tissues. Their approach opens a route to tissue-specific regulation that artificial systems cannot show.
Catalog record
| CREATOR | Arpita Bharadwaj, Joshua N. Curry, Xiao-Tong Su, Romina Barria Maturana, James A. McCormick, David H. Ellison, Isabelle Baconguis |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45135 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |