Telomere length and appendicular lean mass over six years in older adults with overweight or obesity and metabolic syndrome: a prospective cohort study

Héctor Vázquez-Lorente, María Fernández de la Puente, Julio Plaza-Diaz, Nancy Babio, Montse Fitó, Miguel Ángel Martínez-González, Sonia García-Calzón, Amelia Marti del Moral, Jordi Salas-Salvadó · 2026

Read Telomere length and appendicular lean mass over six years in older adults with overweight or obesity and metabolic syndrome: a prospective cohort study by Héctor Vázquez-Lorente, María Fernández de la Puente, Julio Plaza-Diaz, Nancy Babio, Montse Fitó, Miguel Ángel Martínez-González, Sonia García-Calzón, Amelia Marti del Moral, Jordi Salas-Salvadó (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13638864.txt.

Description

Héctor Vázquez-Lorente and eight colleagues report a 2026 cohort study linking telomere length to muscle mass in older adults. Telomeres are caps on chromosome ends that shorten with age, and the study asked whether their length predicts how much lean tissue people keep in their arms and legs.

The sample held 185 adults aged fifty-five to seventy-five with overweight or obesity and metabolic syndrome, followed for six years. Those with longer telomeres at the start kept more lean mass, especially in the legs. The authors caution that an observational link cannot prove telomeres themselves drive muscle aging.

Catalog record

CREATORHéctor Vázquez-Lorente, María Fernández de la Puente, Julio Plaza-Diaz, Nancy Babio, Montse Fitó, Miguel Ángel Martínez-González, Sonia García-Calzón, Amelia Marti del Moral, Jordi Salas-Salvadó
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE44615
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13638864

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