Intact Cell Dissociation of Formalin-Fixed Paraffin-Embedded Colon Tissue Enhances Cell Recovery and Gene Detection in Single-Cell RNA Sequencing
James R. Evans, Alan J. Simmons, Zhengyi Chen, Monica E. Brown, Matthew E. Bechard, Morad C. Malek, Cody N. Heiser, Frank Revetta, M. Kay Washington, Laura P. Hale, Robert J. Coffey, Ken S. Lau · 2026
Read Intact Cell Dissociation of Formalin-Fixed Paraffin-Embedded Colon Tissue Enhances Cell Recovery and Gene Detection in Single-Cell RNA Sequencing by James R. Evans, Alan J. Simmons, Zhengyi Chen, Monica E. Brown, Matthew E. Bechard, Morad C. Malek, Cody N. Heiser, Frank Revetta, M. Kay Washington, Laura P. Hale, Robert J. Coffey, Ken S. Lau (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13635945.txt.
Description
A peer-reviewed research article from Europe PMC (2026). Graphical abstract
Single-cell RNA sequencing (scRNA-seq) has transformed the understanding of tissue heterogeneity at a cellular resolution.1 However, its application to archived human specimens, particularly formalin-fixed paraffin-embedded (FFPE) tissue, remains limited despite the widespread clinical use of FFPE preservation.
Catalog record
| CREATOR | James R. Evans, Alan J. Simmons, Zhengyi Chen, Monica E. Brown, Matthew E. Bechard, Morad C. Malek, Cody N. Heiser, Frank Revetta, M. Kay Washington, Laura P. Hale, Robert J. Coffey, Ken S. Lau |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 16 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |