Multi-stage single-cell atlas of a chordate non-embryonic development unveils dedifferentiating bud founder cells
Marie Lebel, Solène Marchal, Tiphaine Sancerni, Sharon Rabiteau, Pragati Sharma, Tal D Scully, Estelle Balissat, Laurel S Hiebert, Anthony W De Tomaso, Allon M Klein, Alexandre Alié, Stefano Tiozzo · 2026
Read Multi-stage single-cell atlas of a chordate non-embryonic development unveils dedifferentiating bud founder cells by Marie Lebel, Solène Marchal, Tiphaine Sancerni, Sharon Rabiteau, Pragati Sharma, Tal D Scully, Estelle Balissat, Laurel S Hiebert, Anthony W De Tomaso, Allon M Klein, Alexandre Alié, Stefano Tiozzo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13635237.txt.
Description
Marie Lebel and a large team of co-authors built a 2026 cell atlas of how a sea animal grows new bodies without embryos. The animal is a colonial tunicate that buds fresh individuals from the wall of an older one. The shape of this budding was long known, but the cells that start it were not. The team read gene activity in single cells across many stages of bud growth.
Their atlas points to a founder cell group in the surface layer that seems to regain broad growing power. That finding challenges the old idea that a roaming stem cell drives new growth. Other wandering cells in the atlas looked tied to blood or to reproduction instead. The resource may guide work on regrowth in related animals.
Catalog record
| CREATOR | Marie Lebel, Solène Marchal, Tiphaine Sancerni, Sharon Rabiteau, Pragati Sharma, Tal D Scully, Estelle Balissat, Laurel S Hiebert, Anthony W De Tomaso, Allon M Klein, Alexandre Alié, Stefano Tiozzo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 77 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |