Conjugated Polymer‐Microbe Interactions Trigger Regulatory Reprogramming for Enhanced Bioelectrocatalysis

David Ohayon, Yuanmei Liang, Zexuan Wang, Jee Loon Foo, Glenn Quek, Samantha R McCuskey, Zhongxin Chen, Matthew Wook Chang, Guillermo C Bazan · 2026

Read Conjugated Polymer‐Microbe Interactions Trigger Regulatory Reprogramming for Enhanced Bioelectrocatalysis by David Ohayon, Yuanmei Liang, Zexuan Wang, Jee Loon Foo, Glenn Quek, Samantha R McCuskey, Zhongxin Chen, Matthew Wook Chang, Guillermo C Bazan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13634483.txt.

Description

David Ohayon and co-authors wire a living bacterium to a conductive polymer and watch the cell rewrite its own regulation in response. Published in 2026, the study pairs Shewanella oneidensis, a microbe that moves electrons outside its body, with a polymer coated electrode. The setup took up electrons and reduced fumarate far faster than bare controls, with current density up over a hundredfold.

Gene, metabolite, and protein readouts showed coordinated remodeling, not just a passive wire effect. Genes for the electron conduit, energy metabolism, and biofilm formation all rose. A surprise layer emerged in small RNAs: feeding single ones into plain cells copied part of the polymer effect, tripling current. The authors name this RNA layer a new link between materials and microbes.

Catalog record

CREATORDavid Ohayon, Yuanmei Liang, Zexuan Wang, Jee Loon Foo, Glenn Quek, Samantha R McCuskey, Zhongxin Chen, Matthew Wook Chang, Guillermo C Bazan
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE52 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13634483

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