The PRECISE framework: a structured approach to antibiogram interpretation for antimicrobial optimization at the bedside

Claudio Pérez-Oliva, Andrés Giglio, Marcio Borges-Sa · 2026

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Description

A hospital's antibiogram, the chart of which drugs still kill which germs, guides antibiotic choice but is often misread. Claudio Pérez-Oliva, Andrés Giglio, and Marcio Borges-Sa offer a seven-step reading frame called PRECISE. Each letter names an action, from judging the pathogen and its resistance pattern to checking drug levels and setting an endpoint. The frame targets doctors without infectious disease training. Three patient stories show it in use, including one where steps pull against each other.

Guideline-based first choices cut deaths by about a third, and narrowing drugs by culture cuts them further. No earlier frame walks a clinician through one report to a plan, the authors argue. Their mnemonic fills that bedside gap.

Catalog record

CREATORClaudio Pérez-Oliva, Andrés Giglio, Marcio Borges-Sa
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13633490

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