Trends and risk factors associated with hepatitis A severity and mortality in French hospitals: a national population-based study, 2013 to 2024
Anne-Marie Roque-Afonso, Charlotte Mouliade, Lucia Parlati, Nathalie Goutté, Julie Figoni, Samir Bouam, Philippe Sogni, Vincent Mallet, on behalf of the Demosthenes research group · 2026
Read Trends and risk factors associated with hepatitis A severity and mortality in French hospitals: a national population-based study, 2013 to 2024 by Anne-Marie Roque-Afonso, Charlotte Mouliade, Lucia Parlati, Nathalie Goutté, Julie Figoni, Samir Bouam, Philippe Sogni, Vincent Mallet, on behalf of the Demosthenes research group (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13633467.txt.
Description
Anne-Marie Roque-Afonso and seven colleagues, writing for the Demosthenes research group, tracked hepatitis A severity in French hospitals from 2013 to 2024. Hepatitis A is a liver infection spread through contaminated food, water, or close contact. It usually passes mildly in children but hits adults harder. As infections fall across Europe, cases shift to older ages where danger grows. The team used the national hospital discharge database to find every admitted case.
Nearly eight thousand cases were identified, with a median age of thirty. Well over a quarter developed severe disease with organ failure, and a small share died. Older age, male sex, smoking, and existing liver problems raised the odds of severity. Death tied most strongly to heavy overall illness burden and to cirrhosis. Severe disease and death both grew more common in the most recent period. The authors suggest wider, perhaps universal, vaccination deserves consideration.
Catalog record
| CREATOR | Anne-Marie Roque-Afonso, Charlotte Mouliade, Lucia Parlati, Nathalie Goutté, Julie Figoni, Samir Bouam, Philippe Sogni, Vincent Mallet, on behalf of the Demosthenes research group |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| LICENSE | This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |