Skeletal muscle radiodensity as an automated survival predictor in men with metastatic castration-resistant prostate cancer undergoing PSMA-targeted radioligand therapy
Christian Immanuel, Thomas Büttner, Alois M. Sprinkart, Sebastian Nowak, Maike Theis, Jim Küppers, Sibgol Fazeli, Leander Fritzsche, Aland Amin, Dilan Salih, Hojjat Ahmadzadehfar, Florian C. Gärtner, Barbara Kreppel, Rupert Conrad, Manuel Ritter, Markus Essler, Philipp Krausewitz, Milka Marinova · 2026
Read Skeletal muscle radiodensity as an automated survival predictor in men with metastatic castration-resistant prostate cancer undergoing PSMA-targeted radioligand therapy by Christian Immanuel, Thomas Büttner, Alois M. Sprinkart, Sebastian Nowak, Maike Theis, Jim Küppers, Sibgol Fazeli, Leander Fritzsche, Aland Amin, Dilan Salih, Hojjat Ahmadzadehfar, Florian C. Gärtner, Barbara Kreppel, Rupert Conrad, Manuel Ritter, Markus Essler, Philipp Krausewitz, Milka Marinova (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13633348.txt.
Description
Christian Immanuel and a large team of colleagues published this 2026 study of muscle quality as a survival sign in advanced prostate cancer. The patients had metastatic cancer that no longer responded to hormone treatment. All were receiving a targeted radioactive therapy. Software measured muscle density automatically on routine scans of four hundred ten patients, at the level of the lower spine.
Muscle density reflects how much fat has crept into muscle, a marker of poor muscle quality. Patients in the low-density group lived a median of under eight months, compared with over twelve months in the high-density group. The disadvantage held even among patients whose tumors answered the therapy well on blood tests. Density tracked with age and nutrition markers, not with body mass index. The authors propose this scan-derived measure as a free extra forecast for supportive care and treatment planning.
Catalog record
| CREATOR | Christian Immanuel, Thomas Büttner, Alois M. Sprinkart, Sebastian Nowak, Maike Theis, Jim Küppers, Sibgol Fazeli, Leander Fritzsche, Aland Amin, Dilan Salih, Hojjat Ahmadzadehfar, Florian C. Gärtner, Barbara Kreppel, Rupert Conrad, Manuel Ritter, Markus Essler, Philipp Krausewitz, Milka Marinova |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34204 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |