PET-guided early identification of CAR-T candidates in diffuse large b-cell lymphoma: a multidisciplinary expert consensus
Luca Guerra, Domenico Albano, Piera Angelillo, Alice Di Rocco, Mirko Farina, Andrea Farolfi, Vittoria Tarantino, Carlo Visco, Pier Luigi Zinzani · 2026
Read PET-guided early identification of CAR-T candidates in diffuse large b-cell lymphoma: a multidisciplinary expert consensus by Luca Guerra, Domenico Albano, Piera Angelillo, Alice Di Rocco, Mirko Farina, Andrea Farolfi, Vittoria Tarantino, Carlo Visco, Pier Luigi Zinzani (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13633147.txt.
Description
Luca Guerra and eight colleagues published this 2026 expert consensus on using PET scans to find lymphoma patients who should get cell therapy early. The lymphoma type, diffuse large B-cell, often returns after first treatment or never fully responds. CAR-T therapy, which retools a patient's own immune cells, can cure some of these patients, yet referral often comes late. The panel of imaging specialists and blood cancer doctors reviewed evidence on scan timing and measures.
Scans at diagnosis give tumor volume measures that sharpen risk estimates beyond standard scores. Scans during treatment can flag high-risk patients early through standard rating scales and changes in tumor uptake. A final scan after treatment remains essential for judging response. The panel calls the scan a central marker for this disease. They also demand shared standards for scanning and reporting so results match between hospitals.
Catalog record
| CREATOR | Luca Guerra, Domenico Albano, Piera Angelillo, Alice Di Rocco, Mirko Farina, Andrea Farolfi, Vittoria Tarantino, Carlo Visco, Pier Luigi Zinzani |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55070 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |