Ocular immune homeostasis—mechanisms of precise regulation through coordination of the eye, visual system and beyond: a narrative review
Caitlin M Logan, A Sue Menko · 2026
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Description
Caitlin M. Logan and A. Sue Menko review, in 2026, how the eye keeps its immune system in precise balance. Older thinking cast the eye as simply immune-privileged and sealed off, yet newer work shows resident immune cells living in its tissues, necessary for healthy development and for mounting protection after injury.
Regulation turns out to be layered and far-reaching. Events in one eye can stir responses in the other, calming cells such as regulatory T cells and specialised macrophages steer recovery, and even the microbiome feeds into ocular health. The authors argue that grasping these connections, from the eye through the visual system and beyond, opens routes to treatments that preserve sight by restoring balance rather than merely suppressing inflammation.
Catalog record
| CREATOR | Caitlin M Logan, A Sue Menko |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42119 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |