Association between timing of statin treatment after diabetes diagnosis and risk of dementia: a nationwide observational study
Tummas Ternhamar, Mia Ø. Johansen, Børge G. Nordestgaard, Shoaib Afzal · 2026
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Description
Tummas Ternhamar and co-authors study statin timing after diabetes diagnosis in this 2026 paper. Dementia risk climbs in people with type 2 diabetes, and no cure exists. Lowering cholesterol early might help prevent it, so timing could matter.
They used Danish registers for 132,585 adults who developed type 2 diabetes from 2006 to 2019. A trial-like design compared no statin, late start, and early start within one year. Ten-year dementia risk was lowest in the early start group. Early treatment linked to about fifteen percent lower relative risk than no treatment. Late starters sat in between. Death was counted as a competing risk in the estimates.
Catalog record
| CREATOR | Tummas Ternhamar, Mia Ø. Johansen, Børge G. Nordestgaard, Shoaib Afzal |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |