Fast and slow gene expression changes in blood following acute social stress
Hampus Grönvall, Sylvia Abdelhalim, Fara Tabrizi, Sini Ezer, Gamze Yazgeldi Gunaydin, Erik Arner, Jörgen Rosén, Shintaro Katayama, Juha Kere, Fredrik Åhs, Lea Mikkola · 2026
Read Fast and slow gene expression changes in blood following acute social stress by Hampus Grönvall, Sylvia Abdelhalim, Fara Tabrizi, Sini Ezer, Gamze Yazgeldi Gunaydin, Erik Arner, Jörgen Rosén, Shintaro Katayama, Juha Kere, Fredrik Åhs, Lea Mikkola (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13627809.txt.
Description
Researchers in Sweden tracked how genes in blood switch on and off after a short burst of social stress. Stress is known to raise the risk of mental illness and to shift immune cells in the blood. What was less clear is how fast gene activity changes, and which changes fade fast or build slowly. The team gave 27 adults a standard stress test where they speak and do math in front of judges.
Blood was drawn before the test and at four points in the 90 minutes after it. The team found 54 genes whose activity changed with stress. Fast changes peaked at once and linked to killer T cells and related defence cells. Slow changes rose in a straight line and linked to a second cell group, the neutrophils. A signal path tied to IL-12 may link stress to these immune shifts.
Catalog record
| CREATOR | Hampus Grönvall, Sylvia Abdelhalim, Fara Tabrizi, Sini Ezer, Gamze Yazgeldi Gunaydin, Erik Arner, Jörgen Rosén, Shintaro Katayama, Juha Kere, Fredrik Åhs, Lea Mikkola |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |