Goal Location Beta Oscillations and Sharp Wave–Ripples Are Complementary Markers of Learning-Related Changes in Hippocampal–Neocortical Networks
Sameera Shridhar, Zachary M Leveroni, Nan Zhou, Ellie Quattrocchi, Audrey E Kaye, Jaquelin Gutierrez, Amanda Rodríguez León, Leslie M Kay, Jai Y Yu · 2026
Read Goal Location Beta Oscillations and Sharp Wave–Ripples Are Complementary Markers of Learning-Related Changes in Hippocampal–Neocortical Networks by Sameera Shridhar, Zachary M Leveroni, Nan Zhou, Ellie Quattrocchi, Audrey E Kaye, Jaquelin Gutierrez, Amanda Rodríguez León, Leslie M Kay, Jai Y Yu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13626293.txt.
Description
Sameera Shridhar and co-authors listen to two brain regions talk while rats learn a maze. The hippocampus, a memory hub, fires sharp wave-ripples during learning, while the prefrontal cortex, a planning region, was less charted. Electrodes in both regions recorded activity as male rats learned spatial tasks over days, and the team tracked what changed as performance improved.
A beta rhythm near twenty cycles per second swelled in the prefrontal cortex whenever rats reached a goal, growing stronger as they got better, and it tracked the odds of reward. Ripples in the hippocampus moved the other way, shrinking in rate and size as the task grew familiar. The two signals, the authors propose, are partners: one marks fresh encoding, the other growing mastery.
Catalog record
| CREATOR | Sameera Shridhar, Zachary M Leveroni, Nan Zhou, Ellie Quattrocchi, Audrey E Kaye, Jaquelin Gutierrez, Amanda Rodríguez León, Leslie M Kay, Jai Y Yu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |