The impact of macrophage metabolism on idiopathic pulmonary fibrosis development and treatment prospectives
Guangyan Mu, Shan Chong, Jiulong Li, Hanping Wang, Huan Meng, Qian Xiang, Yimin Cui · 2026
Read The impact of macrophage metabolism on idiopathic pulmonary fibrosis development and treatment prospectives by Guangyan Mu, Shan Chong, Jiulong Li, Hanping Wang, Huan Meng, Qian Xiang, Yimin Cui (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13626096.txt.
Description
Guangyan Mu and co-authors present a 2026 review of how macrophage metabolism drives idiopathic pulmonary fibrosis, a scarring lung disease of unknown cause. Macrophages run the disease's environment, and their mix changes as it worsens: the lung's home-grown macrophages dwindle while newcomers from the blood take over, carrying scar-promoting programmes.
The two populations burn fuel differently, and the fibrotic setting rewires both further. That rewiring keeps the scar-building cells active and the matrix piling up. The review maps these metabolic shifts stage by stage and asks which of them drugs could reverse, turning cell fuel choices into treatment prospects for a disease that badly needs them.
Catalog record
| CREATOR | Guangyan Mu, Shan Chong, Jiulong Li, Hanping Wang, Huan Meng, Qian Xiang, Yimin Cui |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 74 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |