Immune checkpoint inhibitor-related endocrinopathies: from immune crosstalk to predictive biomarkers and precision management
Yang Liu, Tong Xu, Zhengyu Chen, Wenhui Zhang, Tao Wang, Weidong Yan, Yanpeng Xie, Haojing Li, Xiaojun Cai · 2026
Read Immune checkpoint inhibitor-related endocrinopathies: from immune crosstalk to predictive biomarkers and precision management by Yang Liu, Tong Xu, Zhengyu Chen, Wenhui Zhang, Tao Wang, Weidong Yan, Yanpeng Xie, Haojing Li, Xiaojun Cai (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13624974.txt.
Description
Yang Liu and eight co-authors wrote this 2026 narrative review on hormone gland damage caused by cancer drugs that free the immune system. These drugs extend lives, but an over-fired immune system can attack the thyroid, the pituitary, the adrenal glands, or the pancreas. Some of that harm never heals, and early warning signs are scarce.
The review pulls together how these injuries arise, from the drug pathways themselves to organ-specific attacks and host traits. Candidate warning markers range from thyroid antibodies and signal profiles to single-cell reads. New tools such as image-based checks, blood biopsies, and layered forecast models are weighed, with their limits named. The authors frame the goal as proactive protection: spot the risk early and watch each patient by their own risk tier.
Catalog record
| CREATOR | Yang Liu, Tong Xu, Zhengyu Chen, Wenhui Zhang, Tao Wang, Weidong Yan, Yanpeng Xie, Haojing Li, Xiaojun Cai |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |