Safety and efficacy of ivabradine in the treatment of patients with acute myocardial infarction: a real-world propensity score matching study

Tianshu Gu, Wanlin Feng, Xian Shao, Jun-Yu Liu, Yu-Kun Zhang, Su-Tao Hu, Wen-Bo Dai, Tong Liu, Kang-Yin Chen · 2026

Read Safety and efficacy of ivabradine in the treatment of patients with acute myocardial infarction: a real-world propensity score matching study by Tianshu Gu, Wanlin Feng, Xian Shao, Jun-Yu Liu, Yu-Kun Zhang, Su-Tao Hu, Wen-Bo Dai, Tong Liu, Kang-Yin Chen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13624656.txt.

Description

Tianshu Gu and co-authors check in 2026 whether a heart rate slowing drug is safe and useful right after a heart attack. The drug slows the heart without weakening its squeeze, which could help a strained heart. Proof for its use in the first phase after an attack is mixed, so the team turned to real world records.

They studied more than 136,000 heart attack patients from 82 hospitals in Tianjin, China, admitted between 2010 and 2024. To make a fair test, they matched patients who got the drug with like patients who did not. Main outcomes were deaths in hospital and heart deaths within a year. Other outcomes covered deaths from any cause and side effects. Large matched studies like this can show if a drug helps in daily care, not just in tight trials.

Catalog record

CREATORTianshu Gu, Wanlin Feng, Xian Shao, Jun-Yu Liu, Yu-Kun Zhang, Su-Tao Hu, Wen-Bo Dai, Tong Liu, Kang-Yin Chen
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE44 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13624656

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