Noninvasive Sampling Reveals Distinct Human Papillomavirus and Immune Signatures Associated With Cytological Abnormalities in People Living With HIV-1
Eva Gruener, Viktoria Menzel, Raffaele Conca, Christof Geldmacher, Ulrich Seybold, Julia Roider · 2026
Read Noninvasive Sampling Reveals Distinct Human Papillomavirus and Immune Signatures Associated With Cytological Abnormalities in People Living With HIV-1 by Eva Gruener, Viktoria Menzel, Raffaele Conca, Christof Geldmacher, Ulrich Seybold, Julia Roider (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13622334.txt.
Description
Eva Gruener and colleagues use gentle swab sampling to study anal HPV in people living with HIV. Their pilot study from twenty twenty-six follows participants over one year. Persistent high-risk HPV drives most anal cancers. People with HIV face that risk at much higher rates.
Fifty-seven participants gave repeated noninvasive samples over time. Tests covered cell changes, virus types, and local immune cells. HPV infection and persistence proved very common in the group. Abnormal cell findings came with more virus types at once. Those cases also showed lower virus amounts per sample. Immune cells near the site looked more active and settled. Swab sampling can reveal this hidden local picture without biopsies.
Catalog record
| CREATOR | Eva Gruener, Viktoria Menzel, Raffaele Conca, Christof Geldmacher, Ulrich Seybold, Julia Roider |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |