Cytokines in narcolepsy type 1: pathogenic relevance, biomarker potential, and future directions
Jingqian Gao, Lijing Jia, Zhenzhen Qu, Xiaoxiao Wang · 2026
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Description
Gao and three co-authors review what immune signal proteins can and cannot tell doctors about narcolepsy type 1. The disorder destroys the brain cells that make a wakefulness chemical, likely through an autoimmune attack. Signals called cytokines may reflect that attack.
Some signals, including IL-6 and two others, track with inflammation and killer T cell activity. Others hint at immune balance and mood symptoms. Yet studies are small, single-center, and hard to compare, with results swayed by body weight, medicines, and sample type. No single cytokine yet earns a place as a diagnostic test. The authors urge combined immune profiles in larger, staged studies.
Catalog record
| CREATOR | Jingqian Gao, Lijing Jia, Zhenzhen Qu, Xiaoxiao Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |