40 Hz biparietal transcranial alternating current stimulation for Alzheimer’s disease: a prospective study
Xiaowei Ma, Mengwei Yuan, Yan Gao, Ziyu Guo, Jiayi Liang, Fangyuan Yan, Shuaixiang Wang, Huiqing Qiu, Sha He, Yang Li, Yuping Wang · 2026
Read 40 Hz biparietal transcranial alternating current stimulation for Alzheimer’s disease: a prospective study by Xiaowei Ma, Mengwei Yuan, Yan Gao, Ziyu Guo, Jiayi Liang, Fangyuan Yan, Shuaixiang Wang, Huiqing Qiu, Sha He, Yang Li, Yuping Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13621547.txt.
Description
Xiaowei Ma and ten colleagues tested gentle electrical stimulation of the scalp as a treatment for mild Alzheimer's disease, in a 2026 prospective trial. Alzheimer's brains show weakened gamma rhythms, the fast brain waves tied to memory. Patients at one Chinese hospital were randomized to real or sham stimulation at forty cycles per second over both parietal lobes, thirty minutes daily for fifteen straight days.
The stimulated group improved on global cognition, memory, language, attention, and executive function, and their behavioral symptom scores fell. The sham group barely moved. Gains held up reasonably at a ten-week check. Brain recordings showed information flowing more strongly from temporal and rear regions toward the front after treatment. Imaging found tighter links inside the default mode network and between it and a control network. The authors call the approach safe and feasible, with effects plausibly running through these network changes.
Catalog record
| CREATOR | Xiaowei Ma, Mengwei Yuan, Yan Gao, Ziyu Guo, Jiayi Liang, Fangyuan Yan, Shuaixiang Wang, Huiqing Qiu, Sha He, Yang Li, Yuping Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50859 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |