Metabolomic characterization and multi-target biological activities of Saponaria pumila and Suaeda confusa: integrating in vitro and in silico approaches
Nilofar Nilofar, Emre Can Buluz, Savas Kaya, Jasmina Glamočlija, Neda Popović, Dejan Stojković, Josef Jeko, Cziaky Zoltan, Nikolaos Tzortzakis, Evren Yildiztugay, Gokhan Zengin · 2026
Read Metabolomic characterization and multi-target biological activities of Saponaria pumila and Suaeda confusa: integrating in vitro and in silico approaches by Nilofar Nilofar, Emre Can Buluz, Savas Kaya, Jasmina Glamočlija, Neda Popović, Dejan Stojković, Josef Jeko, Cziaky Zoltan, Nikolaos Tzortzakis, Evren Yildiztugay, Gokhan Zengin (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13621350.txt.
Description
Nilofar Nilofar and ten colleagues profiled two little-studied plants for chemistry and health-related activity in the lab. Extracts of Saponaria pumila and Suaeda confusa were made with three solvents, and a high-end mass spectrometry method named their compounds. Standard assays then measured antioxidant strength, enzyme blocking, and microbe killing, with computer docking adding targets the wet work cannot see.
The methanol extract of the first plant carried the richest load of phenolics and flavonoids, plant chemicals tied to antioxidant power, and it led most radical-scavenging tests. Water extracts from each plant led on blocking enzymes linked to memory loss and skin darkening, while the second plant's methanol extract topped that pair overall. Microbe tests showed the strongest effects against a foodborne bacterium and a lung fungus, while one hardy hospital bacterium resisted. The authors pitch both plants as raw material for functional products, pending deeper study.
Catalog record
| CREATOR | Nilofar Nilofar, Emre Can Buluz, Savas Kaya, Jasmina Glamočlija, Neda Popović, Dejan Stojković, Josef Jeko, Cziaky Zoltan, Nikolaos Tzortzakis, Evren Yildiztugay, Gokhan Zengin |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 63 KB |
| LICENSE | https://creativecommons.org/licenses/by/3.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |