Conserved trans-regulatory logic and evolving cis-modules drive the diversification of inducible diterpenoid biosynthetic gene clusters across the Oryzoideae
Youming Liu, Shiho Tomiyama, Ikuya Motegi, Naoki Yamamoto, Aiping Zheng, Masaki Mori, Ryoka Kawahara-Miki, Yoshimasa Tsujii, Koji Miyamoto, Hiroyasu Furuumi, Yutaka Sato, Hideaki Nojiri, Kazunori Okada · 2026
Read Conserved trans-regulatory logic and evolving cis-modules drive the diversification of inducible diterpenoid biosynthetic gene clusters across the Oryzoideae by Youming Liu, Shiho Tomiyama, Ikuya Motegi, Naoki Yamamoto, Aiping Zheng, Masaki Mori, Ryoka Kawahara-Miki, Yoshimasa Tsujii, Koji Miyamoto, Hiroyasu Furuumi, Yutaka Sato, Hideaki Nojiri, Kazunori Okada (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13621222.txt.
Description
Youming Liu and co-authors traced how defence chemical gene clusters evolved in rice relatives in a 2026 paper. Rice makes diterpenoid defence compounds when attacked, using genes grouped in clusters. Cluster layout varies across the rice family, yet all share the ability to switch on.
A key switch factor is deeply conserved across rice relatives and wider grasses. By contrast, the control regions of the defence genes have diverged a lot, above all between two genome lineages. Small recurring control modules survive within that divergence. Tests show the number and layout of these modules tune how strongly the switch turns genes on, explaining species-level differences.
Catalog record
| CREATOR | Youming Liu, Shiho Tomiyama, Ikuya Motegi, Naoki Yamamoto, Aiping Zheng, Masaki Mori, Ryoka Kawahara-Miki, Yoshimasa Tsujii, Koji Miyamoto, Hiroyasu Furuumi, Yutaka Sato, Hideaki Nojiri, Kazunori Okada |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |