Selective and Fast Cortisol Sensing in Human Saliva Using Graphene‐Based On‐Chip Field‐Effect Transistors
Bajramshahe Shkodra, Ksenija Arslanova, Eva Fellinger, Tanja Stimpel‐Lindner, Sebastian Klenk, Sebastian Hauk, Kathrin C. Knirsch, Andreas Hirsch, Kristiina Iljin, Tarja K. Nevanen, Annette Schmidt, Georg S. Duesberg · 2026
Read Selective and Fast Cortisol Sensing in Human Saliva Using Graphene‐Based On‐Chip Field‐Effect Transistors by Bajramshahe Shkodra, Ksenija Arslanova, Eva Fellinger, Tanja Stimpel‐Lindner, Sebastian Klenk, Sebastian Hauk, Kathrin C. Knirsch, Andreas Hirsch, Kristiina Iljin, Tarja K. Nevanen, Annette Schmidt, Georg S. Duesberg (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13618521.txt.
Description
Bajramshahe Shkodra and eleven colleagues build a graphene transistor sensor that measures cortisol, the primary stress hormone, directly in human saliva within minutes. Standard hormone testing needs centralized laboratories and slow protocols, which blocks real-time or bedside use. Their chip uses electrolyte-gated graphene field-effect transistors, coated with linker molecules that anchor antibody fragments designed to grab cortisol specifically.
The sensor responded across a wide dynamic range spanning the concentrations found in human saliva, from one hundred femtomolar up to one micromolar. On the same real samples, its readings correlated strongly with the standard laboratory ELISA test run in parallel. Detection is label-free and fast, about ten minutes, which the authors call a major step for miniaturized biosensing. They see the platform extending to other biomarkers and eventually to portable units for real-time stress monitoring outside the laboratory.
Catalog record
| CREATOR | Bajramshahe Shkodra, Ksenija Arslanova, Eva Fellinger, Tanja Stimpel‐Lindner, Sebastian Klenk, Sebastian Hauk, Kathrin C. Knirsch, Andreas Hirsch, Kristiina Iljin, Tarja K. Nevanen, Annette Schmidt, Georg S. Duesberg |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |