The impact of animal models on translating male infertility research from bench to bedside: a narrative review
Shengnan Li, Tengfei Chen, Hongyan Chen, Boxian Gao, Chongfu Zhong · 2026
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Description
Shengnan Li and co-authors review how animal models help move male fertility research toward real care, in work published in 2026. Male infertility has many causes, and its inner workings are still not fully known. Models let teams copy human illness in the lab, trace how it starts, and screen new drugs before human trials.
The review sorts models by how the harm is induced, from drugs and hormone blockers to heat and blocked veins. It maps the harm paths each model copies, such as oxygen strain, swelling, and cell death. It also names drug targets the models have revealed, to guide the search for new care.
Catalog record
| CREATOR | Shengnan Li, Tengfei Chen, Hongyan Chen, Boxian Gao, Chongfu Zhong |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 74 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |