Emerging role of stem cells and tissue engineering in oculoplastic surgery

Manu Saini, Sunil Gaba, Usha Singh, Kulbhushan Saini, Parul C. Gupta, Manpreet Singh, Talvir Sidhu, Pankaj Gupta · 2026

Read Emerging role of stem cells and tissue engineering in oculoplastic surgery by Manu Saini, Sunil Gaba, Usha Singh, Kulbhushan Saini, Parul C. Gupta, Manpreet Singh, Talvir Sidhu, Pankaj Gupta (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13614735.txt.

Description

Manu Saini and colleagues review in 2026 how stem cells and tissue engineering are changing oculoplastic surgery, the repair of eyelids, eye sockets, and nearby structures. Stem cells can grow into replacement tissue and release signals that help wounds heal. The review covers fat-derived stem cells, lab-reprogrammed stem cells, and mesenchymal stem cells from marrow and other tissues.

Engineers combine these cells with soft scaffolds and growth factors to build stand-ins for eyelid skin, the stiff plate inside the lid, the eye's surface lining, and tear glands. Current uses include restoring lost volume around the eye, rebuilding lids, and fitting empty eye sockets. Benefits over grafts include less harm at the donor site. Work is moving toward tear glands grown in the lab and lids that can move, though hard problems remain.

Catalog record

CREATORManu Saini, Sunil Gaba, Usha Singh, Kulbhushan Saini, Parul C. Gupta, Manpreet Singh, Talvir Sidhu, Pankaj Gupta
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29876
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13614735

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