Larvicidal Activity, GC–MS Profiling and Multitarget Molecular Docking of Essential Oils from Cymbopogon citratus, Tanacetum cinerariifolium and Salvia rosmarinus Against Anopheles arabiensis
Eric Kibagendi Osoro, Bernard Mwiti Kithetu, Alex Muthengi, Njogu M Kimani, Bulelwa Audrey Ngcangatha, Fidelis Ngugi, Mojeed Adedoyin Agoro, Nicholas Rono, Alessandro Pedretti, Kemal Husnu Can Baser · 2026
Read Larvicidal Activity, GC–MS Profiling and Multitarget Molecular Docking of Essential Oils from Cymbopogon citratus, Tanacetum cinerariifolium and Salvia rosmarinus Against Anopheles arabiensis by Eric Kibagendi Osoro, Bernard Mwiti Kithetu, Alex Muthengi, Njogu M Kimani, Bulelwa Audrey Ngcangatha, Fidelis Ngugi, Mojeed Adedoyin Agoro, Nicholas Rono, Alessandro Pedretti, Kemal Husnu Can Baser (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13610486.txt.
Description
Eric Kibagendi Osoro leads a ten-author team testing plant oils against malaria mosquito larvae. With resistance and green worries shadowing chemical sprays, plant oils offer a greener option. The team extracted oils from lemongrass, pyrethrum flower, and rosemary, dosed Anopheles arabiensis larvae with them. Each oil's chemistry was profiled, and found compounds were docked virtually against two proteins mosquito larvae need.
Every oil killed more larvae as dose rose. Pyrethrum oil was strongest, with a half-lethal dose of 511.0 milligrams per liter; lemongrass followed at 602.7 in the same units. Chemistry differed sharply: sesquiterpenes dominated pyrethrum oil, while monoterpenes ruled the other two. In the docking screen, most compounds bound well to both target proteins, and farnesol stood out, also passing insecticide-likeness tests. The authors credit teamwork among oil components hitting matching targets, and promote pyrethrum and lemongrass as greener larval treatments.
Catalog record
| CREATOR | Eric Kibagendi Osoro, Bernard Mwiti Kithetu, Alex Muthengi, Njogu M Kimani, Bulelwa Audrey Ngcangatha, Fidelis Ngugi, Mojeed Adedoyin Agoro, Nicholas Rono, Alessandro Pedretti, Kemal Husnu Can Baser |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |