Neurotoxicity of Synthetic Cannabinoid Receptor Agonist Cumyl-PINACA: An In Vitro Study on Rat Cortical Neurons and Astrocytes
Damijana Mojca Jurič, Klara Bulc Rozman, Metoda Lipnik-Štangelj, Dušan Šuput, Miran Brvar · 2026
Read Neurotoxicity of Synthetic Cannabinoid Receptor Agonist Cumyl-PINACA: An In Vitro Study on Rat Cortical Neurons and Astrocytes by Damijana Mojca Jurič, Klara Bulc Rozman, Metoda Lipnik-Štangelj, Dušan Šuput, Miran Brvar (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13610142.txt.
Description
Juric and co-authors tested a synthetic cannabinoid on rat brain cells in two thousand twenty-six. Street cannabinoids can be far stronger than plant cannabis. Their cell-level harm is poorly mapped. One compound, a cumyl-type agent, was applied in culture. Both neurons and their astrocyte partners were exposed. A wide dose range spanned the exposures.
Metabolic activity and mitochondria were tracked closely. Cell shape and death rates were scored as well. Blocker drugs probed which receptors drove the harm. Several receptor paths were tested one by one. Damage patterns pointed to specific signaling routes. Such maps help emergency doctors read poisonings. They also flag which compounds deserve tighter control.
Catalog record
| CREATOR | Damijana Mojca Jurič, Klara Bulc Rozman, Metoda Lipnik-Štangelj, Dušan Šuput, Miran Brvar |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |