Association Between Any Circulating ANCA Positivity at Diagnosis and Subsequent End-Stage Kidney Disease in Microscopic Polyangiitis and Granulomatosis with Polyangiitis
Jang Woo Ha, Jeong Yeop Whang, Oh Chan Kwon, Yong-Beom Park, Sang-Won Lee · 2026
Read Association Between Any Circulating ANCA Positivity at Diagnosis and Subsequent End-Stage Kidney Disease in Microscopic Polyangiitis and Granulomatosis with Polyangiitis by Jang Woo Ha, Jeong Yeop Whang, Oh Chan Kwon, Yong-Beom Park, Sang-Won Lee (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13609817.txt.
Description
Jang Woo Ha and co-authors ask whether a positive antibody test at diagnosis forecasts kidney failure in two vessel-inflaming diseases, in a 2026 study. The team reviewed 271 patients with microscopic polyangiitis or granulomatosis with polyangiitis at one hospital. Nearly nine in ten tested positive for ANCA antibodies. Over follow-up, about one in six patients died and one in five reached end-stage kidney disease.
Kidney failure clearly clustered in the antibody-positive group, whose kidney survival curves ran lower. Yet once age, sex, disease type, and starting kidney function were accounted for, the antibody result alone no longer predicted the outcome. Starting kidney health, it seems, carries the signal.
Catalog record
| CREATOR | Jang Woo Ha, Jeong Yeop Whang, Oh Chan Kwon, Yong-Beom Park, Sang-Won Lee |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |