Individualizing Perioperative Analgesia: Patient-Specific Determinants of Postoperative Pain and Opioid-Related Outcomes
Sarah Kazemeini, Ryan Shih, Sunny Zhang, Raphael Cohen, Nathaniel LaBarre, Moonis Ghani, George Tsao · 2026
Read Individualizing Perioperative Analgesia: Patient-Specific Determinants of Postoperative Pain and Opioid-Related Outcomes by Sarah Kazemeini, Ryan Shih, Sunny Zhang, Raphael Cohen, Nathaniel LaBarre, Moonis Ghani, George Tsao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13609513.txt.
Description
Sarah Kazemeini and six co-authors wrote this 2026 narrative review on tailoring pain relief around surgery to each patient. Pain after surgery and the need for strong pain drugs vary a lot, even for the same operation. The review weighs how sex, age, frailty, long-term pain, prior drug use, and mental state shape pain, drug response, and recovery.
The authors searched two databases for reviews, trials, and guidelines on adult surgical patients. The proof was mixed across groups and operations, and no single trait always foretold pain or drug need. Women faced more nausea after surgery, while claims about sex gaps in pain were uneven. Older and frail patients were more prone to sedation, slowed breathing, and confusion from the drugs. The review urges care plans that weigh the whole patient.
Catalog record
| CREATOR | Sarah Kazemeini, Ryan Shih, Sunny Zhang, Raphael Cohen, Nathaniel LaBarre, Moonis Ghani, George Tsao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |