Identifying MASLD Patients with MASH or Significant Fibrosis: The Role of Lower ALT Thresholds
Ying Ma, Hang Yang, Yuanyuan Zhao, Ping Han, Yuying Jin, Lili Zhao, Jie Liu, Jia Li · 2026
Read Identifying MASLD Patients with MASH or Significant Fibrosis: The Role of Lower ALT Thresholds by Ying Ma, Hang Yang, Yuanyuan Zhao, Ping Han, Yuying Jin, Lili Zhao, Jie Liu, Jia Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13607483.txt.
Description
Ying Ma and co-authors published a liver study in 2026 on lower blood test cutoffs for spotting serious fatty liver disease. A common blood enzyme, ALT, guides checks for liver swelling and scarring. Yet the severe forms can occur even when ALT looks normal by standard cutoffs. The team compared standard and lower cutoffs against biopsy results, the reference test.
The study drew on just over four hundred patients at two hospitals in Tianjin who had liver biopsies. Among patients with normal ALT by the standard cutoff, about half still had the severe swelling form or major scarring. The lower cutoff was linked to the severe form on its own, but its test accuracy was limited, so the authors call for more study.
Catalog record
| CREATOR | Ying Ma, Hang Yang, Yuanyuan Zhao, Ping Han, Yuying Jin, Lili Zhao, Jie Liu, Jia Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |