Study on the Therapeutic Effects of Ginsenoside Rh2 in Asthma Improvement
Yuming Wang, Xiaohua Li, Dongming Xue, Tianxia Sun, Yu Zhao · 2026
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Description
Yuming Wang and four co-authors test ginsenoside Rh2, a ginseng compound, as a treatment for asthma in cell and animal models. The compound has wide biological activity, yet its asthma mechanisms were unclear. A bacterial toxin cell model and an ovalbumin sensitized mouse model are treated at three dose levels each.
Rh2 lowers a panel of pro inflammatory signals and raises anti inflammatory ones in both models. Key pathway proteins in Toll like receptor and NF-kB signaling fall as well. Transcript and metabolite profiling point to TNF signaling, cytokine receptor interaction, and two metabolic pathways as main targets. The joint evidence supports Rh2 as a candidate for asthma therapy development.
Catalog record
| CREATOR | Yuming Wang, Xiaohua Li, Dongming Xue, Tianxia Sun, Yu Zhao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |