Integrated Transcriptomic Analysis Identifies a Candidate INHBA/Activin A-Associated Macrophage–MuSC Communication Axis in Human Skeletal Muscle Ageing
Xuanchen Liu, Zehui Li, Yutong Yuan, Nuo Si, Ningbei Yin · 2026
Read Integrated Transcriptomic Analysis Identifies a Candidate INHBA/Activin A-Associated Macrophage–MuSC Communication Axis in Human Skeletal Muscle Ageing by Xuanchen Liu, Zehui Li, Yutong Yuan, Nuo Si, Ningbei Yin (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13607107.txt.
Description
Xuanchen Liu and co-authors studied why human muscle grows weaker with age, in work published in 2026. Old muscle heals more slowly, and the role of immune cells that move into muscle is still unclear.
The team combined several kinds of gene data from human muscle, plus a second group of older adults for a check. Old muscle showed more signs of swelling and fewer signs linked to energy use. One cell signal, tied to a protein made by inflamed immune cells, stood out as a link to stem cells in the muscle. In lab tests, that signal slowed the growth of new muscle cells, and a blocking drug reduced the effect.
Catalog record
| CREATOR | Xuanchen Liu, Zehui Li, Yutong Yuan, Nuo Si, Ningbei Yin |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |