The Upregulation of Two CYP6 Genes Is Associated with the Response to Broflanilide in Bactrocera dorsalis (Hendel, 1912) (Diptera: Tephritidae)
Bo Liu, Si-Yi Chen, Zhi-Hong Li, Shao-Kun Guo · 2026
Read The Upregulation of Two CYP6 Genes Is Associated with the Response to Broflanilide in Bactrocera dorsalis (Hendel, 1912) (Diptera: Tephritidae) by Bo Liu, Si-Yi Chen, Zhi-Hong Li, Shao-Kun Guo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13607031.txt.
Description
Bo Liu, Si-Yi Chen, Zhi-Hong Li, and Shao-Kun Guo study how a major fruit fly pest answers a new insecticide, in a 2026 paper. The pest, the oriental fruit fly, is a quarantine threat to orchards worldwide.
Adults that survived a half-lethal dose of the insecticide broflanilide were compared with untreated flies. Gene readings from gut and fat tissue showed two detox genes switched on far more strongly after exposure. Silencing either gene made the insecticide kill far more flies. Computer docking suggests both gene products can bind the drug's active breakdown form. The pair are thus candidates for the fly's defense system. Knowing them helps track resistance before it spreads in the field.
Catalog record
| CREATOR | Bo Liu, Si-Yi Chen, Zhi-Hong Li, Shao-Kun Guo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |