Post-Synthetic Surface Quaternization of Agarose Cryogels: Optimizing Structural Integrity and Broad-Spectrum Growth Inhibition

Ahmet Erdem, Elif Beyza Eren, Farouk Segujja, Elif Kale Bakir, Yonca Yuzugullu Karakus, Suheda Ercek, Tugba Dispinar Gezer · 2026

Read Post-Synthetic Surface Quaternization of Agarose Cryogels: Optimizing Structural Integrity and Broad-Spectrum Growth Inhibition by Ahmet Erdem, Elif Beyza Eren, Farouk Segujja, Elif Kale Bakir, Yonca Yuzugullu Karakus, Suheda Ercek, Tugba Dispinar Gezer (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13606618.txt.

Description

Ahmet Erdem and co-authors give seaweed-based wound gels a germ-killing surface without wrecking their sponge structure, in a 2026 study. Agarose cryogels suit wound care but are biologically inert, and harsh chemistry can collapse their pores. Their fix treats the finished gel: a quaternary ammonium compound is bonded onto the surface under alkaline conditions.

Tuning time, temperature, and gel strength produced two grades of modification, confirmed by surface analysis. Porosity actually rose while the pore network stayed intact. The stronger grade hit Escherichia coli and Staphylococcus aureus hardest and left human vein cells about eighty-eight percent viable in extract tests. The authors propose the non-leaching scaffolds for chronic wound dressings.

Catalog record

CREATORAhmet Erdem, Elif Beyza Eren, Farouk Segujja, Elif Kale Bakir, Yonca Yuzugullu Karakus, Suheda Ercek, Tugba Dispinar Gezer
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE55 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13606618

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