Transcriptome Analysis of Deltamethrin Resistance Mechanisms in Aedes aegypti Populations from Metro Manila, Philippines
Marc Ralph M. Solomon, Ma. Anita M. Bautista · 2026
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Description
Solomon and Bautista read in 2026 the gene activity of mosquitoes in Metro Manila that resist a common spray. The mosquito spreads dengue and other viral diseases, and spray resistance weakens control. Two local groups were tested for resistance to the spray deltamethrin.
Both groups proved resistant, with lethal doses that shifted a bit after low dose exposure. Gene reads showed higher activity in three detox gene families than in a spray free control group. Path maps also flagged drug handling routes. Spot checks by a second gene method matched the reads well. The results name likely routes by which local mosquitoes beat the spray.
Catalog record
| CREATOR | Marc Ralph M. Solomon, Ma. Anita M. Bautista |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |