Biomarkers of Treatment-Escalation Risk by Obesity Status in Pediatric Asthma: A Development and External Validation Cohort Study
Serdar Göktaş, Mehmet Şirin Kaya · 2026
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Description
Serdar Goktas and Mehmet Kaya ask in 2026 whether body weight changes which blood marks warn of worse asthma in children. Four marks were tracked against sustained step-ups in treatment, the sign that asthma is slipping from control. Their build set held 292 children, split among no-allergy controls, normal-weight asthma, and asthma with obesity.
Seventy-five children needed a lasting step-up. In the obese group, one mark more than doubled the risk per set rise, they report; in the normal-weight group a different mark led. The pattern was then tested, unchanged, on 180 children from a second city. Marks that work in one weight class may mislead in another, so weight-aware cutoffs could sharpen asthma care.
Catalog record
| CREATOR | Serdar Göktaş, Mehmet Şirin Kaya |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |