Longitudinal PET/CT-Derived Body Composition Changes During Systemic Therapy in Patients with Lung Cancer
Bojun Wang, Song Xue, Jueya Zhang, Yuqi Wang, Hanfei Zhang, Chengwen Zheng, Huiyuan Zhang, Yang Yang, Marcus Hacker, Xiang Li · 2026
Read Longitudinal PET/CT-Derived Body Composition Changes During Systemic Therapy in Patients with Lung Cancer by Bojun Wang, Song Xue, Jueya Zhang, Yuqi Wang, Hanfei Zhang, Chengwen Zheng, Huiyuan Zhang, Yang Yang, Marcus Hacker, Xiang Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13605957.txt.
Description
Bojun Wang and co-authors track body composition during lung cancer therapy in a 2026 study. Host metabolism may steer how long treatment holds progression back. Scans taken for tumor monitoring also capture body tissues. Paired scans before and after therapy enabled change analysis.
Fifty-three patients with confirmed lung cancer were included retrospectively. Muscle, fat depots, and organ metabolism were quantified. Thirty-one patients progressed during follow-up. Median progression-free time was seven months. Muscle volume fell significantly by follow-up imaging. One deep fat depot grew significantly meanwhile. Gaining torso fat linked to lower progression risk after adjustment. That link vanished in a timing-aligned subset, however. The authors treat that reversal cautiously in interpretation. Metabolic network analysis explored wider patterns. Body change during therapy carries prognostic hints. Prospective confirmation is clearly needed. Scan byproducts may become biomarkers.
Catalog record
| CREATOR | Bojun Wang, Song Xue, Jueya Zhang, Yuqi Wang, Hanfei Zhang, Chengwen Zheng, Huiyuan Zhang, Yang Yang, Marcus Hacker, Xiang Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |