mRNA Vaccines as Novel Immunotherapeutic Approaches in Gastrointestinal Cancers
Michele Ghidini, Federica Novazzi, Nerina Denaro, Angelica Petrillo, Margherita Ratti, Massimiliano Salati, Roberta Malvaso, Lorenza Di Marco, Alessandro Parisi, Jens Claus Hahne · 2026
Read mRNA Vaccines as Novel Immunotherapeutic Approaches in Gastrointestinal Cancers by Michele Ghidini, Federica Novazzi, Nerina Denaro, Angelica Petrillo, Margherita Ratti, Massimiliano Salati, Roberta Malvaso, Lorenza Di Marco, Alessandro Parisi, Jens Claus Hahne (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13605912.txt.
Description
Ghidini, Novazzi, Denaro, and a team of co-authors review mRNA vaccines as a treatment for cancers of the gut. Their review is from two thousand twenty-six. These vaccines moved fast from use against infection into cancer care. Forms built for one patient aim to rouse T cells that attack that patient's tumor.
Early trials in bowel and pancreatic cancer showed fair safety and clear immune response. Yet hard blocks stand in the way of routine use. Tumors vary a lot, can hide from the immune system, and the right targets are hard to pick. The vaccine platform must also stay stable. The review covers delivery routes and pairing these vaccines with checkpoint drugs. It ends with steps that may bring them into daily care.
Catalog record
| CREATOR | Michele Ghidini, Federica Novazzi, Nerina Denaro, Angelica Petrillo, Margherita Ratti, Massimiliano Salati, Roberta Malvaso, Lorenza Di Marco, Alessandro Parisi, Jens Claus Hahne |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |