Mechanisms of Serotonergic Modulation of Glial Cell Functions in the Recovery Period After Spinal Cord Injury
E. V. Nikiforova, A. Vetlugina, S. P. Konovalova, Y. I. Sysoev, P. E. Musienko · 2026
Read Mechanisms of Serotonergic Modulation of Glial Cell Functions in the Recovery Period After Spinal Cord Injury by E. V. Nikiforova, A. Vetlugina, S. P. Konovalova, Y. I. Sysoev, P. E. Musienko (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13605824.txt.
Description
Nikiforova and co-authors review how serotonin shapes glial cells after spinal cord injury in a paper from 2026. Recovery stalls because severed axons fail to regrow their myelin coats. Scarring, chronic inflammation, and fragile myelin-forming cells block repair. The brain's serotonin system reaches all three glial cell types.
Precursor cells and mature myelin cells carry several serotonin receptors. Switching them on can speed maturation, halt movement, or trigger cell death, depending on context. Astrocytes and microglia, the scar and immune players, answer to serotonin too. The review maps each receptor's effects cell by cell. Tuning serotonin signals might one day reopen the repair window. Spinal injury needs every lever it can get.
Catalog record
| CREATOR | E. V. Nikiforova, A. Vetlugina, S. P. Konovalova, Y. I. Sysoev, P. E. Musienko |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 101 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |