Candidate Regulatory Relationship and Expression Correlation Between miR-33a-5p and ANK3 in Chronic Myeloid Leukemia
Nurgul Kar, Sema Misir, Serap Ozer Yaman, Osman Akidan, Ceylan Hepokur, Yuksel Aliyazicioglu · 2026
Read Candidate Regulatory Relationship and Expression Correlation Between miR-33a-5p and ANK3 in Chronic Myeloid Leukemia by Nurgul Kar, Sema Misir, Serap Ozer Yaman, Osman Akidan, Ceylan Hepokur, Yuksel Aliyazicioglu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13605770.txt.
Description
Nurgul Kar and co-authors investigate a possible control link between a small RNA and a scaffold gene in chronic myeloid leukemia, in a 2026 study. This leukemia drives white blood cells to multiply without control. MicroRNAs are tiny regulators that tune gene activity after transcription. The candidate pair is miR-33a-5p and the gene ANK3.
Public expression data first suggested the two move in opposite directions. Lab measurements in patient material checked that pattern directly. The team probed whether the microRNA binds and represses the gene. A confirmed link would add a new control layer to leukemia biology. It might also suggest RNA-based drug angles. The study is early-stage, framed as a candidate relationship. Replication in larger cohorts comes next.
Catalog record
| CREATOR | Nurgul Kar, Sema Misir, Serap Ozer Yaman, Osman Akidan, Ceylan Hepokur, Yuksel Aliyazicioglu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |