Narrative Review of the Role of Reactive Oxygen Species in Allergic Rhinitis
Jeongmin Lee, Su Young Jung, Hye Ok Kim, Jae Min Lee, Manish Kumar Singh, Sung Soo Kim, Jeon Gang Doo, Seung Geun Yeo · 2026
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Description
Jeongmin Lee and co-authors review the role of reactive oxygen species in allergic rhinitis in a 2026 paper. These aggressive oxygen molecules were once seen as mere exhaust from cell metabolism. Evidence now casts them as active signals inside the allergic inflammation network that makes noses itch, swell, and run.
The review searched five databases and kept seventeen studies spanning two decades. Patient studies show disturbed redox balance in blood, with more fat oxidation damage, though few measured the nose itself. Lab studies agree that allergens raise these molecules in nasal and immune cells, where they batter the lining barrier and feed inflammatory switches. The authors conclude the molecules help drive the disease, not just mark it, which makes antioxidant strategies worth testing for hay fever relief.
Catalog record
| CREATOR | Jeongmin Lee, Su Young Jung, Hye Ok Kim, Jae Min Lee, Manish Kumar Singh, Sung Soo Kim, Jeon Gang Doo, Seung Geun Yeo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |