Shear Wave Elastography for Non-Invasive Assessment of Skin Involvement in Systemic Sclerosis
Xuesong Liu, Hanlin Yin, Wanyi Lin, Chenhan Jia, Fenglin Wu, Xinyu Li, Chunhua Wu, Ruru Guo, Liangjing Lu, Lixin Jiang · 2026
Read Shear Wave Elastography for Non-Invasive Assessment of Skin Involvement in Systemic Sclerosis by Xuesong Liu, Hanlin Yin, Wanyi Lin, Chenhan Jia, Fenglin Wu, Xinyu Li, Chunhua Wu, Ruru Guo, Liangjing Lu, Lixin Jiang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13605320.txt.
Description
Xuesong Liu and co-authors test an ultrasound method for stiff skin in a 2026 study. Systemic sclerosis is an immune disease that scars and hardens skin. Doctors grade skin involvement by touch, a rough scale. The team asked whether shear wave elastography, which measures stiffness with sound, could grade skin more exactly and tell patients from healthy people.
The study enrolled 78 patients and 30 healthy controls. High-frequency ultrasound measured skin thickness and stiffness at fingers, hands, and forearms. Patients with the widespread form had thicker skin at all sites. Stiffness values ran higher in patients across sites. In a biopsy subset, stiffness tracked the collagen share in the skin. The method separated patients from controls with good accuracy, best at the fingers.
Catalog record
| CREATOR | Xuesong Liu, Hanlin Yin, Wanyi Lin, Chenhan Jia, Fenglin Wu, Xinyu Li, Chunhua Wu, Ruru Guo, Liangjing Lu, Lixin Jiang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |