Fontan Failure: Current State of the Art in Mechanical Circulatory Support and Transplantation
Rosaria Barracano, Gabriele De Palma, Claudia Montanaro, Vito Casale, Nunzia Borrelli, Antonella Bruna Cutrì, Micol Rebonato, Ippolita Altobelli, Gianfranco Butera, Giancarlo Scognamiglio, Berardo Sarubbi · 2026
Read Fontan Failure: Current State of the Art in Mechanical Circulatory Support and Transplantation by Rosaria Barracano, Gabriele De Palma, Claudia Montanaro, Vito Casale, Nunzia Borrelli, Antonella Bruna Cutrì, Micol Rebonato, Ippolita Altobelli, Gianfranco Butera, Giancarlo Scognamiglio, Berardo Sarubbi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13605104.txt.
Description
Rosaria Barracano and co-authors review the current state of care when a Fontan circulation begins to fail, in a 2026 paper. The Fontan operation reroutes blood flow for children born with a single working heart chamber, and it has rewritten their life stories. Over time, though, many patients slide into failure: without a pump under the lungs, pressure in the veins stays high, output falls, and organs suffer one by one.
The review explains those mechanisms and then grades the advanced options. Assist devices that boost the heart are gaining ground, both as a bridge to transplant and, in chosen cases, as lasting support, though the Fontan plumbing complicates their use. Transplant remains the only definitive fix despite its surgical difficulty. The authors call for sharper risk sorting and timely moves to advanced care, handled by coordinated teams.
Catalog record
| CREATOR | Rosaria Barracano, Gabriele De Palma, Claudia Montanaro, Vito Casale, Nunzia Borrelli, Antonella Bruna Cutrì, Micol Rebonato, Ippolita Altobelli, Gianfranco Butera, Giancarlo Scognamiglio, Berardo Sarubbi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |