Decoding Mitophagy in Breast Cancer: Biological Mechanisms, Dual Roles, and Clinical Implications
Silvia Zunico, Giorgia Pisano, Cristina Della Bella, Maria Zeb, Luisa Cirillo, Martina Autiero, Raffaella Di Monda, Carmen Pacilio, Alessandra Leone, Michelino De Laurentiis, Stefania Cocco · 2026
Read Decoding Mitophagy in Breast Cancer: Biological Mechanisms, Dual Roles, and Clinical Implications by Silvia Zunico, Giorgia Pisano, Cristina Della Bella, Maria Zeb, Luisa Cirillo, Martina Autiero, Raffaella Di Monda, Carmen Pacilio, Alessandra Leone, Michelino De Laurentiis, Stefania Cocco (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13605078.txt.
Description
Silvia Zunico and co-authors present a 2026 review of mitophagy, the cell's cleanup of worn mitochondria, in breast cancer. Failed cleanup lets damaged power plants leak reactive waste that scars DNA and seeds tumors. Yet the same cleanup can help grown tumors bend their fuel use, keep stem-like traits, and reshape nearby immune cells. The review sorts when the process guards and when it feeds the disease, by stage, setting, and tumor type.
That split role makes the process a tempting but tricky drug target. Dialing it up or down could starve tumors or break their drug shields, if the timing is right. The authors map what proof is still missing before clinics can dose it with care.
Catalog record
| CREATOR | Silvia Zunico, Giorgia Pisano, Cristina Della Bella, Maria Zeb, Luisa Cirillo, Martina Autiero, Raffaella Di Monda, Carmen Pacilio, Alessandra Leone, Michelino De Laurentiis, Stefania Cocco |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |