Survival-Associated Molecular and Epigenetic Alterations in Endocervical Adenocarcinoma: An Exploratory TCGA Multi-Omics Cohort Study
Yasemin Cakir, Zeynep Bayramoglu · 2026
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Description
Yasemin Cakir and Zeynep Bayramoglu report an exploratory study from two thousand twenty-six on survival-linked molecular changes in a cancer of the cervix called endocervical adenocarcinoma. Which molecular traits separate patients who live from those who die was largely unknown for this cancer type. Public atlas data let the team scan many layers at once.
They studied twenty-seven cases with mutation, copy number, gene activity, protein, and methylation data, plus invasion patterns read by two pathologists. One protein stood out: patients with higher levels of it lived longer. Eight genes differed in methylation between the living and deceased groups, most of them more heavily marked in the deceased. Enrichment checks tied the changes to known pathways.
Catalog record
| CREATOR | Yasemin Cakir, Zeynep Bayramoglu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |